Volume No. 12 Issue No.: 4 Page No.: 474-478 April-June 2018

 

INVITRO SCREENING OF ANTIFUNGAL ACTIVITY OF LEAF EXTRACT OF Vitex negundo

 

Dassani S.*, Sharma T. K. and Pandey M. M.

Department of Botany and Industrial Microbiology, Bipin Bihari College, Jhansi, U.P. (INDIA)

 

Received on : September 29, 2017

 

ABSTRACT

 

Vitex negundo is a medicinal plant of family Verbenaceae which is commonly found throughout India and is used in traditional medicines. The present study was undertaken to screen potential antifungal activity of the extract of leaves of V. negundo against three dermatophytes i.e. Epidermophyton, Microsprorum and Trichophyton. The leaf extract was prepared by crushing the leaves in methanol, ethanol and distilled water as a solvent. These extracts were evaluated for their antifungal activity against Epidermophyton, Microsporum and Trichophyton on Sabouraud Dextrose Agar media (SDA) plates by using agar well diffusion method. The plates were incubated at 3520C for 24 hrs. Then diameter of zone of inhibition was measured. Best antifungal activity was observed against Trichophyton with ethanol as a solvent and the least activity was observed against Epidermophyton with distilled water as a solvent.

 

Keywords : Epidermophyton, Trichophyton, Microsporum, Vitex negundo, Antifungal activity

 

 

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